/ P-cadherin Content for 51吃瓜黑料 Davis en /news/outside-signaling-shows-route-cancer-cells <p>A new study shows how an anticancer drug triggers an 鈥渙utside in鈥� signal that gets it sucked into a cancer cell. The work, published Jan. 29 in <a href="https://www.nature.com/articles/s41467-025-56478-6">Nature Communications</a>, reveals a new signaling mechanism that could be exploited for delivering other drugs.&nbsp;</p><p>Many malignant cancers overexpress a protein called P-cadherin, which is embedded in the cell membrane. Because cancer cells have a lot of P-cadherin sticking out of their surface, the protein has been targeted for drug development.&nbsp;</p> February 04, 2025 - 9:08am Andy Fell /news/outside-signaling-shows-route-cancer-cells