Mouse Biology Program Content

NIH Renews Knockout Mouse Project for 3rd Time

Andy Fell — August 15, 2022 - 10:00am

The University of California, Davis, has been awarded just over $12 million from the National Institutes of Health under the third and final five-year phase of the Knockout Mouse Phenotyping Project, or KOMP2. 51�ԹϺ�� Davis is the lead organization in a consortium involving a partnership with The Centre for Phenogenomics in Toronto.

Grant to Create Humanized Mice for HIV Studies

Andy Fell — August 12, 2022 - 2:41pm

Creating a new type of ‘humanized mouse’ that can be infected with HIV is the goal of new project at the Mouse Biology Program of the University of California, Davis. The work is funded with a grant of nearly $500,000 from the National Institutes of Health.

A Map of Mouse Brain Metabolism in Aging

Andy Fell — October 15, 2021 - 4:09pm

The first atlas of metabolites in the mouse brain has been published by a team led by 51�ԹϺ�� Davis researchers. The dataset includes 1,547 different molecules across 10 brain regions in male and female laboratory mice from adolescence through adulthood and into advanced old age. The work is published Oct. 15 in the Nature Communications. The complete dataset is publicly available at https://mouse.atlas.metabolomics.us/.

NIH Grant to Create Humanized Mice Susceptible to COVID-19

Andy Fell — August 03, 2020 - 1:36pm

The National Institutes of Health has awarded a grant of $1.2 million to the Mouse Biology Program at the University of California, Davis, to create mice that are susceptible to the COVID-19 virus, and to distribute them to researchers.

The goal is to create mice that can be used to reproduce human COVID-19 disease, said Kent Lloyd, director of the Mouse Biology Program and professor in the Department of Surgery at the 51�ԹϺ�� Davis School of Medicine.

COVID-19 Vaccine With Patch Delivery Technology Enters Preclinical Testing at 51�ԹϺ�� Davis

Andy Fell — April 29, 2020 - 4:49pm

Verndari Inc., a biopharmaceutical company, announced today (April 29) that it will begin preclinical testing this week at the University of California, Davis, Mouse Biology Program to evaluate a potential vaccine and delivery system for COVID-19.

Mouse Genome Studies Show Disease Models and Sex Differences

Andy Fell — June 26, 2017 - 3:48pm

Two major studies by international teams published today (June 26) show the value and potential of genetically modified mice in biomedical research — and also the pitfalls of conducting research with subjects of only one sex. Researchers at the 51�ԹϺ�� Davis Mouse Biology Program collaborated on both studies, published in the journals Nature Genetics and Nature Communications.